Saturday, 5 August 2017

CRISPR patent battle in Europe takes a 'wild' twist with surprising player


Controversial CRISPR gene-editing could update day by day insulin injections in diabetes sufferers new research shows.Mice whose pores and skin cells are genetically altered to express the glucose-regulating hormone GLP1 benefit around half of as tons weight whilst eating a excessive-fats weight loss plan as other animals a look at found.They also expand less insulin resistance the research provides. Excess weight and reduced insulin sensitivity are both related to diabetes onset.These results are maintained for around three months suggesting genetically-enhancing talent cells ought to replace insulin injections in diabetes http://www.workpost.com/gdnther6654_profile.aspx patients.CRISPR technology precisely changes small parts of the genetic code. Unlike different comparable tools CRISPR completely turns on or off genes on the DNA level. Critics warn the era can be used to choose toddlers hair color or eventual peak. Controversial CRISPR gene-editing should replace every day insulin injections in diabetes patients RELATED ARTICLES Previous 1 Next Want to live strong in vintage age? Eating protein 3 times a... Carrying too much weight? You can be improper for an... Mind-controlled listening to aids filter out historical past noise by... Mother-of- sues clinic for amputating her leg after she... Share this text Share forty one stocks WHY IS GENE EDITING CONTROVERSIAL? Gene-editing technology inclusive of CRISPR can exactly cut and paste sections of DNA to both take away undesirable genes or insert applicable ones.Some have recommended the era could be used to cast off detrimental genes from children before they are born inclusive of those that reason Huntington s sickness or hereditary blindness.Yet the era could also be used to insert genes for preferred traits such as blond hair or above-average height.If science s knowledge of genetics improves the era may additionally one day be used to insert genes that encode positive skills such as  musical capacity. How the have a look at changed into performed Researchers from the University of Chicago used CRISPR to edit the gene that expresses the glucose-regulating hormone GLP-1.GLP-1 works to trigger the release of insulin and the following elimination of excess glucose from the blood however it simplest lasts for a brief time.The researchers edited the gene to lengthen its interest.Such a gene was inserted into mouse pores and skin cells inside the lab which were then transplanted into mice who had been being fed a excessive-fats food regimen. Edited cells make mice gain less weight and insulin resistance Results screen that mice given the genetically-altered skin cells benefit round half  of as a good deal weight as those no longer transplanted with them.These mice additionally develop much less insulin resistance. Excess weight and decreased insulin sensitivity are both hazard factors for diabetes.Similar effects passed off while the researchers edited human skin cells and transplanted them into hairless mice.Overall these outcomes lasted for three months which indicates the gene-edited cells may be an opportunity to insulin injections.Dr Timothy Kieffer a diabetes professional at the University of British Columbia stated: I do  are expecting that gene and mobile treatments will ultimately replace repeated injections for the remedy of chronic sicknesses. The findings had been published in the journal Cell Stem Cell. Crispr-Cas9 gene-editing approach acts as tiny scissors to eliminate small quantities of a geneHow does CRISPR gene-modifying era work?CRISPR era precisely changes small components of the genetic code.Unlike other comparable equipment CRISPR completely activates or off genes at the DNA stage.The DNA reduce referred to as a double-strand smash intently mimics the kinds of mutations that occur naturally for example after persistent solar publicity.Yet unlike UV rays which could result in random genetic alterations CRISPR causes a mutation at a particular region.When cellular machinery repairs the DNA damage it removes a small snip of DNA.In this way researchers can exactly turn off specific genes. The technology mixed DNA-slicing enzyme with a programmable molecular guide permitting scientists to tell the enzyme where to cut. (Image: Reuters) Last yr Sichuan University China stated its first a success test the use of gene-enhancing. Using a method called CRISPR-Cas9 scientists have been able to inject a gene in a affected person with lung cancer. The generation combined DNA-reducing enzyme with a programmable molecular guide allowing scientists to tell the enzyme where to cut. The US consistent with Nature has long past a step in advance. On Wednesday scientists on the gene expression lab of La Jolla California announced their success in editing human embryos using CRISPR. In this case the scientists used seventy five zygotes to correct an inherited heart condition. The utility of this have a look at may be confined to heart however once permitted the era can be used to correct genetic beginning-defects. This is just the first of the scientific trials at US and Chinese universities specially with gene-editing being considered a one-prevent solution for the entirety from most cancers to coronary heart diseases and diabetes. While this may help increase existence expectancy it additionally leaves the door open for a gene-race. And in the absence of any straight forward research defining who can do what it is going to be difficult to check its effect. More vital gene remedy additionally opens a debate on ethics with countries sooner or later gambling with the concept of fashion designer toddlers. Although the studies at present can most effective cope with the problem of genetic sicknesses and eye color variations we may also still be far from developing superhumans or clothier infants there wishes to be a consensus on what can be executed in the purview of technological know-how. There is a want for China US and different international locations to take the lead in constructing a consensus on ethics earlier than the arena delves into gene-editing in addition. Breaking News SRINAGAR: Three humans were today injured when Army employees allegedly opened hearth at a group of stone- pelting youths in Bandipora district of Kashmir police stated. A group of youths pelted stones on Army motors which had been passing through S K Bala locality in Sumbol region of Bandipora this morning a police authentic said. He stated the Army employees allegedly opened fire to disperse the mob ensuing in injuries to a few humans. The injured were mentioned a health facility here for treatment he delivered. A similar incident befell at Harnag in Anantnag district but there had been no casualties inside the alleged Army firing there the legit stated. PTI MIJ AAR 08051135 NNNN By: Express Web Desk five 2017 3:26 pm Jammu and Kashmir: Police recovered 3 AK-47 rifles from the militants. (Source: ANI) Related News IAS officer removed as Deputy Commissioner after objectionable pix cross viralPolice rescues two teenage boys who wanted to sign up for militancyJ Islamabad: Pakistan s new Prime Minister Shahid Khaqan Abbasi on Friday formed a cabinet filled with allies of toppled leader Nawaz Sharif in a reshuffle that appears aimed at bolstering support ahead of general elections due in mid-2018.Ishaq Dar a powerful finance minister returns in the same role despite a criminal investigation ordered against him by the Supreme Court.Another staunch Sharif ally Khawaja Asif is to be Foreign Minister after having simultaneously run the ministries of defence and power.The cabinet has almost doubled in size to 47 members sworn in during a televised ceremony after a reading from the Koran holy book in the mainly Muslim nation of 190 million people. It s a massive cabinet said Pakistani writer and analyst Zahid Hussain. It shows that it s all about the next election. But no decision appears to have yet been made by the ruling Pakistan Muslim League-Nawaz (PML-N) party over whether Abbasi will stay as premier or step down after a brief period to make way for Sharif s brother Shahbaz as outlined previously.Nawaz Sharif resigned last week after the Supreme Court disqualified him for not declaring a source of income he denies receiving. But he retains control of PML-N and put forward Abbasi as temporary prime minister until Shahbaz becomes eligible to take over by winning a parliamentary by-election.Since Abbasi s election however the party leadership no longer seems sure about that plan as some fear Shahbaz s departure from his position as chief minister of eastern Punjab state could weaken the party s grip on a core base of voters.Pakistan s mix of political parties means that whoever wins Punjab which is home to more than half the country s population is likely to form the next government.Former petroleum minister Abbasi the co-founder of a budget airline has vowed to run an efficient government but has indicated major decisions will flow from Nawaz cementing the view of the toppled leader as the power behind the throne.Abbasi is a staunch Nawaz ally having been by his side for most of his political career. The cabinet was formed after several discussions between them and Nawaz s allies.There are 28 federal ministers and 19 state ministers in the new cabinet almost double Sharif s 25-strong cabinet when he swept the 2013 polls.Abbasi will also head a new energy ministry that merges the petroleum and power portfolios.Ahsan Iqbal head of a commission tasked with building the Beijing-funded 57 billion China-Pakistan Economic corridor has been appointed Interior Minister.The opposition has criticised the PML-N s focus on large infrastructure projects as vote-focused measures that saddle Pakistan with debt at the expense of schools and hospitals. If they carry on with Nawaz Sharif s policies the country will go deeper into debt said Naeem Ul Haq of the opposition Pakistan Tehreek-i-Insaf (PTI) party.FEUDAL POLITICSTo shore up the voter base in Punjab Abbasi has added five politicians from prominent families that command huge vote banks in the south of the region seen as pivotal to the next poll.A feudal structure in much of rural Pakistan allows powerful families to wield huge influence and command voter allegiances often easily switched in a nation where political parties are driven more by powerful figureheads than ideology.The inclusion of five politicians from south Punjab aimed to nail down their loyalties ahead of the 2018 contest analyst Hussain said. There was always been a fear or a concern they would jump ship if the government seems weak he added.Darshan Lal also became the first Hindu minister in more than two decades when Abbasi appointed him to lead coordination between four Pakistani provinces a government official said.Under Sharif the PML-N has also courted the minority vote using symbolic gestures at odds with its conservative base. Thomson Reuters 2017(Except for the headline this story has not been edited by NDTV staff and is published from a syndicated feed.) ISLAMABAD: The Cabinet of Pakistan s new Prime Minister Shahid Khaqan Abbasi was sworn in today with media reports saying that Khawaja Asif has been appointed the country s first full-time foreign minister since 2013. President Mamnoon Hussain administered the oath to the new members at a ceremony at the President House in Islamabad. The new Cabinet largely retained old faces but some new leaders were included as ministers and ministers of state. There was some confusion about the size of the Cabinet as state-run PTV reported that it included 28 ministers and 18 ministers of state while Geo TV reported that 28 ministers and 19 ministers of state have taken oath. There was no formal announcement so far on the portfolios. Media reports said that portfolios of several ministers from the previous Nawaz Sharif dispensation have been changed. According to the reports Khawaja Asif has been appointed as the country s first full-time foreign minister since 2013 when the Pakistan Muslim League-Nawaz party came to power. https://live.vcita.com/site/gdnther  Asif had the dual charge of the defence ministry and the water and power ministry in the previous government. Ahsan Iqbal has been appointed the interior minister and former trade minister Khurrum Dastigir Khan was given the defence portfolio. However the powerful former interior minister Nisar Ali Khan has been excluded from the new Cabinet as he refused to join due to differences with the party leadership the reports said. Ishaq Dar retained the finance ministry portfolio despite Supreme Court orders to register corruption cases against him. Daniyal Aziz Talal Chaudhry Arshad Leghari and Junaid Anwar Chaudhry were among the new faces to take oath. Two days ago Prime Minister Abbasi had delayed the formation of the Cabinet after meeting Sharif at the ousted premier s Murree residence. Sharif has been staying in Murree since he vacated the official residence earlier this week after the Supreme Court disqualified him in connection with the Panama Papers scandal. The transition to the new Cabinet has taken exactly seven days since Sharif s ouster on July 28. Islamabad: The first cabinet meeting held by newly elected Prime Minister Shahid Khaqan Abbasi on Friday asserted moral and diplomatic support for Kashmir.Newly appointed Prime Minister Shahid Khaqan Abbasi promised to continue the journey of progress and democracy initiated by former prime minister Nawaz Sharif who was unseated by the Supreme Court on charges of corruption. Abbasi is said to be a close confidant of Sharif.File image of Shahid Abbasi. APAbbasi emphasised that all projects including the China-Pakistan Economic Corridor would continue and added that the fight against terrorism would be carried out in letter and spirit . India has often said the terror problem internally faced by Pakistan comes from its encouragement to cross-border terrorism.Abbasi vowed to complete the developmental plans of 10 years in the next 10 months.He asked all ministers to present their short-term goals to the cabinet.Abbasi is expected to be replaced by Shahbaz Sharif Chief Minister of Punjab province and brother of Nawaz Sharif after getting elected to the National Assembly in a by-election within two months. On Tuesday former Petroleum Minister Shahid Khaqan Abbasi was sworn in as the Prime Minister of Pakistan replacing Nawaz Sharif who has been disqualified by the Supreme Court over dishonesty following a probe into the Panama Papers leaks. While Abbasi s comfortable win following the National Assembly vote was expected the ruling Pakistan Muslim League-Nawaz (PML-N) is interpreting it as a resounding triumph that reaffirms the party s parliamentary clout. However despite Abbasi s claims that he s no bench warmer the party s plan is to eventually allow Shahbaz Sharif to take over as the Prime Minister after contesting a by-election on the seat vacated by his elder brother Nawaz. World news in pictures 89 show all World news in pictures 1/89 August 4 2017 A family claiming to be from Haiti drag their luggage over the US-Canada border into Canada from Champlain New York U.S. August 3 2017. Reuters 2/89 August 4 2017 A disabled man prepares to cast his vote at a polling station in Kigali Rwanda August 4 2017 Reuters 3/89 August 4 2017 ATTENTION EDITORS -People carry the body of Yawar Nissar a suspected militant who according to local media was killed during a gun battle with Indian security forces at Herpora village during his funeral in south Kashmir s Anantnag district August 4 2017. Reuters 4/89 August 4 2017 A general view shows a flooded area in Sakon Nakhon province Thailand August 4 2017. Reuters 5/89 3rd August 2017 A plane landed in Sao Joao Beach killing two people in Costa da Caparica Portugal August 2 2017 Reuters 6/89 3rd August 2017 Hermitage Capital CEO William Browder waits to testify before a continuation of Senate Judiciary Committee hearing on alleged Russian meddling in the 2016 presidential election on Capitol Hill in Washington U.S. July 27 2017 Reuters 7/89 3rd August 2017 TOPSHOT - Moto taxi driver hold flags of the governing Rwanda Patriotic Front s at the beginning of a parade in Kigali on August 02 2017. Incumbent Rwandan President Paul Kagame will close his electoral campaigning ahead of the August 4 presidential elections which he is widely expected to win giving him a third term in office AFP 8/89 3rd August 2017 TOPSHOT - Migrants wait to be rescued by the Aquarius rescue ship run by non-governmental organisations (NGO) SOS Mediterranee and Medecins Sans Frontieres (Doctors Without Borders) in the Mediterranean Sea 30 nautic miles from the Libyan coast on August 2 2017. AFP 9/89 2 August 2017 Two children hold a placard picturing a plane as they take part in a demonstration in central Athens outside the German embassy with others refugees and migrants to protest against the limitation of reunification of families in Germany on August 2 2017. AFP 10/89 2 August 2017 Flames erupt as clashes break out while the Constituent Assembly election is being carried out in Caracas Venezuela July 30 2017. REUTERS/Carlos Garcia Rawlins Reuters 11/89 2 August 2017 People in the village of Gabarpora carry the remains of Akeel Ahmad Bhat a civilian who according to local media died following clashes after two militants were killed in an encounter with Indian security forces in Hakripora in south Kashmir s Pulwama district August 2 2017. REUTERS/Danish Ismail Reuters 12/89 2 August 2017 - Incumbent Rwandan President Paul Kagame gestures as he arrives for the closing rally of the presidential campaign in Kigali on August 2 2017 while supporters greet him. Rwandans go the polls on August 4 2017 in a presidential election in which strongman Paul Kagame is widely expected to cruise to a third term in office. AFP 13/89 30 July 2017 Soldiers of China s People s Liberation Army (PLA) get ready for the military parade to commemorate the 90th anniversary of the foundation of the army at Zhurihe military training base in Inner Mongolia Autonomous Region China. REUTERS 14/89 29 July 2017 Cyclists at the start of the first stage of the Tour de Pologne cycling race over 130km from Krakow s Main Market Square Poland EPA 15/89 28 July 2017 Israeli border guards keep watch as Palestinian Muslim worshippers pray outside Jerusalem s old city overlooking the Al-Aqsa mosque compound Ahmad Gharabli/AFP 16/89 28 July 2017 A supporter of Pakistan s Prime Minister Nawaz Sharif passes out after the Supreme Court s decision to disqualify Sharif in Lahore Reuters/Mohsin Raza 17/89 27 July 2017 Australian police officers participate in a training scenario called an Armed Offender/Emergency Exercise held at an international passenger terminal located on Sydney Harbour Reuters/David Gray 18/89 27 July 2017 North Korean soldiers watch the south side as the United Nations Command officials visit after a commemorative ceremony for the 64th anniversary of the Korean armistice at the truce village of Panmunjom in the Demilitarized Zone (DMZ) dividing the two Koreas Reuters/Jung Yeon-Je 19/89 26 July 2017 Bangladeshi commuters use a rickshaw to cross a flooded street amid heavy rainfall in Dhaka. Bangladesh is experiencing downpours following a depression forming in the Bay of Bengal. Munir Uz Zaman/AFP 20/89 26 July 2017 The Soyuz MS-05 spacecraft for the next International Space Station (ISS) crew of Paolo Nespoli of Italy Sergey Ryazanskiy of Russia and Randy Bresnik of the U.S. is transported from an assembling hangar to the launchpad ahead of its upcoming launch at the Baikonur Cosmodrome in Baikonur Kazakhstan Reuters/Shamil Zhumatov 21/89 25 July 2017 A protester shouts at U.S. President Donald Trump as he is removed from his rally with supporters in an arena in Youngstown Ohio Reuters 22/89 23 July 2017 Indian supporters of Gorkhaland chant slogans tied with chains during a protest march in capital New Delhi. Eastern India s hill resort of Darjeeling has been rattled at the height of tourist season after violent clashes broke out between police and hundreds of protesters of the Gorkha Janmukti Morcha (GJM) a long-simmering separatist movement that has long called for a separate state for ethnic Gorkhas in West Bengal. The GJM wants a new separate state of Gorkhaland carved out of eastern West Bengal state of which Darjeeling is a part. Sajjad Hussain/AFP/Getty Images 23/89 23 July 2017 Demonstrators clash with riot security forces while rallying against Venezuela s President Nicolas Maduro s government in Caracas Venezuela. The banner on the bridge reads It will be worth it Reuters 24/89 22 July 2017 The Heathcote river as it rises to high levels in Christchurch New Zealand. Heavy rain across the South Island in the last 24 hours has caused widespread damage and flooding with Dunedin Waitaki Timaru and the wider Otago region declaring a state of emergency. Getty Images 25/89 22 July 2017 A mourner prays at a memorial during an event to commemorate the first anniversary of the shooting spree that one year ago left ten people dead including the shooter in Munich Germany. One year ago 18-year-old student David S. shot nine people dead and injured four others at and near a McDonalds restaurant and the Olympia Einkaufszentrum shopping center. After a city-wide manhunt that caused mass panic and injuries David S. shot himself in a park. According to police David S. who had dual German and Iranian citizenship had a history of mental troubles. Getty 26/89 21 July 2017 Palestinians react following tear gas that was shot by Israeli forces after Friday prayer on a street outside Jerusalem s Old City Reuters/Ammar Awad 27/89 21 July 2017 Ousted former Thai prime minister Yingluck Shinawatra greets supporters as she arrives at the Supreme Court in Bangkok Thailand Reuters/Athit Perawongmetha 28/89 20 July 2017 Marek Suski of Law and Justice (PiS) (C) party scuffles with Miroslaw Suchon (2nd L) of Modern party (.Nowoczesna) as Michal Szczerba of Civic Platform (PO) (L) party holds up a copy of the Polish Constitution during the parliamentary Commission on Justice and Human Rights voting on the opposition s amendments to the bill that calls for an overhaul of the Supreme Court in Warsaw Reuters 29/89 20 July 2017 A firefighter stands near a grass fire as he prepares to defend a home from the Detwiler fire in Mariposa California Reuters 30/89 19 July 2017 Michael Lindell CEO of My Pillow reacts as U.S. President Donald Trump attends a Made in America roundtable meeting in the East Room of the White House Reuters 31/89 18 July 2017 Giant pandas lie beside ice blocks at Yangjiaping Zoo in Chongqing China. Yangjiaping Zoo provided huge ice blocks for giant pandas to help them remove summer heat Getty Images 32/89 18 July 2017 People ride camels in the desert in Dunhuang China as stage 10 of The Silkway Rally continues AFP/Getty Images 33/89 18 July 2017 17th FINA World Aquatics Championships in Budapest Hungary. Team North Korea practice under coach supervision REUTERS 34/89 17 July 2017 IAAF World ParaAthletics Championships - London Britain - July 17 2017 Reuters/Henry Browne 35/89 17 July 2017 Workers check power lines during maintenance work in Laian in China s eastern Anhui province AFP/Getty Images 36/89 17 July 2017 Russia Kamaz s driver Dmitry Sotnikov co-drivers Ruslan Akhmadeev and Ilnur Mustafin compete during the Stage 9 of the Silk Way 2017 between Urumqi and Hami China Franck Fife/AFP/Getty Images 37/89 17 July 2017 Australian Prime Minister Malcolm Turnbull talks with Special Operations Command soldiers during a visit to the Australian Army s Holsworthy Barracks in western Sydney AAP/Brendan Esposito/via Reuters 38/89 16 July 2017 Men in traditional sailor costumes celebrate after carrying a statue of the El Carmen Virgin who is worshipped as the patron saint of sailors into the Mediterranean Sea during a procession in Torremolinos near Malaga Spain Reuters/Jon Nazca 39/89 16 July 2017 People participate in a protest in front of the Sejm building (the lower house of the Polish parliament) in Warsaw Poland. The demonstration was organized by Committee for the Defense of Democracy (KOD). Members and supporters of the KOD and opposition parties protested against changes in the judicial law and the Supreme Court EPA 40/89 16 July 2017 People prepare to swim with a portrait of late Chinese Chairman Mao Zedong on the bank of the Yangtze River in Yichang Hubei province China to celebrate the 51st anniversary of Chairman Mao swimming in the Yangtze River. REUTERS 41/89 15 July 2017 A woman takes a selfie picture with her mobile phone next to the statue of Omer Halisdemir in Istanbul in front of a memorial with the names of people killed last year during the failed coup attempt . AFP/Getty Images 42/89 14 July 2017 French President Emmanuel Macron gestures next to US President Donald Trump during the annual Bastille Day military parade on the Champs-Elysees avenue in Paris. AFP/Getty Images 43/89 13 July 2017 Philippine National Police chief Ronald Bato Dela Rosa holds an M60 machine gun during a Gun and Ammunition show at a mall in Mandaluyong city metro Manila Philippines Reuters 44/89 13 July 2017 Ukrainian President Petro Poroshenko and European Commission President Jean-Claude Juncker embrace before the EU-Ukraine summit in Kiev Ukraine Reuters 45/89 13 July 2017 US President Donald Trump (R) and First Lady Melania Trump disembark form Air Force One upon arrival at Paris Orly airport on July 13 2017 beginning a 24-hour trip that coincides with France s national day and the 100th anniversary of US involvement in World War I Saul Loeb/AFP/Getty Images 46/89 12 July 2017 Iraqis walk on a damaged street in west Mosul a few days after the government s announcement of the liberation of the embattled city from Islamic State (IS) group fighters Getty 47/89 12 July 2017 Iraqi boys wash a vehicle in west Mosul a few days after the government s announcement of the liberation of the embattled city from Islamic State (IS) group fighters Fadel Senna/AFP/Getty Images 48/89 11 July 2017 Afghan policeman pour fuel over jerry cans containing confiscated acetic acid before setting it alight on the outskirts of Herat. Some 15 000 liters of acetic acid often mixed with heroin were destroyed by counter narcotics police Hoshang Hashimi/AFP 49/89 10 July 2017 Police from the anti-terror squad participate in an anti-terror performance among Acehnese dancers during a ceremony to commemorate the 71st anniversary of the Indonesian police corps in Banda Aceh AFP/Getty Images 50/89 11 July 2017 Residents stand amid the debris of their homes which were torn down in the evicted area of the Bukit Duri neighbourhood located on the Ciliwung river banks in Jakarta Bay Ismoyo/AFP 51/89 11 July 2017 Boys play cricket at a parking lot as it rains in Chandigarh India Reuters/Ajay Verma 52/89 10 July 2017 Turkey s President Recep Tayyip Erdogan speaks at the 22nd World Petroleum Congress (WPC) in Istanbul AFP 53/89 10 July 2017 New Mongolia s president Khaltmaa Battulga takes an oath during his inauguration ceremony in Ulaanbaatar Mongolia Reuters 54/89 10 July 2017 US army 1st Division US air force US Navy and US Marines march down the Champs Elysees with the Arc de Triomphe in the background in Paris during a rehearsal of the annual Bastille Day military parade AFP 55/89 9 July 2017 Participants run ahead of Puerto de San Lorenzo s fighting bulls during the third bull run of the San Fermin festival in Pamplona northern Spain. Each day at 8:00 am hundreds of people race with six bulls charging along a winding 848.6-metre (more than half a mile) course through narrow streets to the city s bull ring where the animals are killed in a bullfight or corrida during this festival immortalised in Ernest Hemingway s 1926 novel The Sun Also Rises and dating back to medieval times and also featuring religious processions folk dancing concerts and round-the-clock drinking. AFP/Getty Images 56/89 8 July 2017 Iraqi women who fled the fighting between government forces and Islamic State (IS) group jihadists in the Old City of Mosul cry as they stand in the city s western industrial district awaiting to be relocated AFP 57/89 8 July 2017 US President Donald Trump arrives for another working session during the G20 summit in Hamburg northern Germany AFP/Getty Images 58/89 7 July 2017 People climb up on a roof to get a view during riots in Hamburg northern Germany where leaders of the world s top economies gather for a G20 summit AFP/Getty Images 59/89 6 July 2017 Anti-capitalism activists protest in Hamburg where leaders of the world s top economies will gather for a G20 summit. AFP/Getty 60/89 7 July 2017 A military helicopter rescues people trapped on the roof of the Ministry of Finance by an intense fire in San Salvador AFP/Getty Images 61/89 6 July 2017 Donald Trump arrives to deliver a speech at Krasinski Square in Warsaw Poland. AP 62/89 6 July 2017 A firefighter conducts rescue operations in an area damaged by heavy rain in Asakura Japan. Reuters 63/89 6 July 2017 Crowds gather for the start of the San Fermin festival in Pamplona Spain. AFP 64/89 5 July 2017 A member of the Iraqi security forces runs with his weapon during a fight between Iraqi forces and Islamic State militants in the Old City of Mosul Iraq. 65/89 5 July 2017 A U.S. MGM-140 Army Tactical Missile is fired during the combined military exercise between the U.S. and South Korea against North Korea at an undisclosed location in South Korea A.P 66/89 4 July 2017 North Korean Leader Kim Jong Un looks on during the test-fire of inter-continental ballistic missile Hwasong-14 Reuters 67/89 4 July 2017 Russian President Vladimir Putin (R) shakes hands with his Chinese counterpart Xi Jinping during a signing ceremony following the talks at the Kremlin Reuters 68/89 3 July 2017 Belarussian servicemen march during a military parade as part of celebrations marking the Independence Day in Minsk Belarus Reuters 69/89 3 July 2017 Ambulance cars and fire engines are seen near the site where a coach burst into flames after colliding with a lorry on a motorway near Muenchberg Germany Reuters 70/89 28 June 2017 An aerial view shows women swimming in the Yenisei River on a hot summer day with the air temperature at about 32 degrees Celsius (89.6 degrees Fahrenheit) outside Krasnoyarsk Siberia Russia June 28 2017 Reuters 71/89 2 July 2017 Protesters demonstrating against the upcoming G20 economic summit ride boats on Inner Alster lake during a protest march in Hamburg Germany. Hamburg will host the upcoming G20 summit and is expecting heavy protests throughout. Getty Images 72/89 27 June 2017 Investigators work at the scene of a car bomb explosion which killed Maxim Shapoval a high-ranking official involved in military intelligence in Kiev Ukraine June 27 2017 Reuters 73/89 1 July 2017 Protesters carry a large image of jailed Chinese Nobel Peace laureate Liu Xiaobo as they march during the annual pro-democracy protest in Hong Kong. Thousands joined an annual protest march in Hong Kong hours after Chinese President Xi Jinping wrapped up his visit to the city by warning against challenges to Beijing s sovereignty. AP 74/89 30 June 2017 Jockey Andrea Coghe of Selva (Forest) parish rides his horse during the first practice for the Palio Horse Race in Siena Italy June 30 2017 Reuters 75/89 30 June 2017 A man takes pictures with a phone with a Union Flag casing after Chinese President Xi Jinping (not pictured) inspected troops at the People s Liberation Army (PLA) Hong Kong Garrison as part of events marking the 20th anniversary of the city s handover from British to Chinese rule in Hong Kong China June 30 2017 Reuters 76/89 29 June 2017 A protester against U.S. President Donald Trump s limited travel ban approved by the U.S. Supreme Court holds a sign next to protesters supporting the ban in New York City U.S. June 29 2017 Reuters 77/89 29 June 2017 Israeli Air Force Efroni T-6 Texan II planes perform at an air show during the graduation of new cadet pilots at Hatzerim base in the Negev desert near the southern Israeli city of Beer Sheva AFP/Getty Images 78/89 28 June 2017 A woman gestures next to people spraying insecticide on a vehicle during a mosquito-control operation led by Ivory Coast s National Public and Health Institute in Bingerville near Abidjan where several cases of dengue fever were reported AFP/Getty Images 79/89 27 June 2017 A Libyan coast guardsman watches over as illegal immigrants arrive to land in a dinghy during the rescue of 147 people who attempted to reach Europe off the coastal town of Zawiyah 45 kilometres west of the capital Tripoli on June 27 2017. More than 8 000 migrants have been rescued in waters off Libya during the past 48 hours in difficult weather conditions Italy s coastguard said on June 27 2017 AFP/Getty Images 80/89 26 June 2017 A man leaves after voting in the Mongolian presidential election at the Erdene Sum Ger (Yurt) polling station in Tuul Valley. Mongolians cast ballots on June 26 to choose between a horse breeder a judoka and a feng shui master in a presidential election rife with corruption scandals and nationalist rhetoric AFP/Getty Images 81/89 26 June 2017 People attend Eid al-Fitr prayers to mark the end of the holy fasting month of Ramadan at a play ground in the suburb of Sale Morocco REUTERS 82/89 25 June 2017 A plain-clothes police officer kicks a member of a group of LGBT rights activist as Turkish police prevent them from going ahead with a Gay Pride annual parade on 25 June 2017 in Istanbul a day after it was banned by the city governor s office. AFP/Getty Images 83/89 25 June 2017 Pakistan army soldiers stands guard while rescue workers examine the site of an oil tanker explosion at a highway near Bahawalpur Pakistan. An overturned oil tanker burst into flames in Pakistan on Sunday killing more than one hundred people who had rushed to the scene of the highway accident to gather leaking fuel an official said. AP 84/89 24 June 2017 Rescue workers search for survivors at the site of a landslide that occurred in Xinmo Village Mao County Sichuan province China REUTERS 85/89 23 June 2017 Student activists shout anti martial law slogans during a protest in Manila on June 23 2017 AFP/Getty Images 86/89 23 June 2017 A diver performs from the Pont Alexandre III bridge into the River Seine in Paris France June 23 2017 as Paris transforms into a giant Olympic park to celebrate International Olympic Days with a variety of sporting events for the public across the city during two days as the city bids to host the 2024 Olympic and Paralympic Games Reuters 87/89 23 June 2017 Debris and smoke are seen after an OV-10 Bronco aircraft released a bomb during an airstrike as government troops continue their assault against insurgents from the Maute group who have taken over parts of Marawi city Philippines June 23 2017 Reuters 88/89 22 June 2017 Russian President Vladimir Putin (C) stands under pouring rain during a wreath-laying ceremony marking the 76th anniversary of the Nazi German invasion by the Kremlin walls in Moscow on June 22 2017 AFP/Getty Images 89/89 22 June 2017 Smoke rises following a reported air strike on a rebel-held area in the southern Syrian city of Daraa on June 22 2017 AFP/Getty Images This would mean the younger Sharif giving up his current position as the Chief Minister of Punjab Pakistan s most populous province which could be taken up by his son (and Nawaz s nephew) Hamza Shahbaz Sharif. This shakeup in the centre and Punjab expected to materialise by the end of September would reaffirm the Sharif family s control over the federal and Punjab governments and indeed the ruling party named after them. It also inadvertently sends out a clear message to the party MNA (National Assembly members) and MPAs (Provincial Assembly members): none of them merit even a nine-month stint as the Prime Minister or Chief Minister ahead of next year s elections. While it underscores dynastic politics throttlehold over Pakistan the reshuffle also accentuates the PML-N s desperation as the ruling party faces challenges as diverse as judicial probes military intrusion an opposition gaining momentum and disgruntled senior party members threatening defection. In this regard maintaining the Sharif brand for the ruling party is as much a nepotistic disgrace as an editorial in Pakistan s leading English newspaper Dawn dubbed it as it s the PML-N s version of the doctrine of necessity aimed at preventing party disintegration on the brink of the general elections. At a time when the opposition Pakistan People s Party (PPP) still has to maintain brand Bhutto four decades after the party founder Zulfikar Ali Bhutto s judicial execution just so it can cling on to its depreciating vote bank one can imagine the impact having a non-Sharif at the helm could have on the PML-N next year. This vicious circle of dynastic politics and the popular trend to vote for names and not ideas is also true for the Pakistan Tehrik-e-Insaf (PTI) whose chairman Imran Khan the chief orchestrator of the probe that eventually ousted Nawaz Sharif is a demagogue who has successfully wooed a heretofore untapped vote bank towards brand Khan which is synonymous with change . Read more The ousting of Nawaz Sharif is a double-edged sword for Pakistan Khan s rhetoric which conspicuously steers clear of holding the country s all-powerful Army leadership accountable for their many misadventures bears an uncanny resemblance to the surge of alt-right parties in the West in its fixation with antagonism towards a misrepresentated status quo. With farcical intraparty elections underscoring the undemocratic nature of the leading political parties in Pakistan it is ironically the Islamist Jamaat-e-Islami (JI) with its long-stated ambition of formalising Sharia law that is the sole prominent ideological party devoid of individual or familial influence. Many argue that dynastic politics which has particularly marred South Asia isn t as high on the priority list of issues facing Pakistan especially considering that the Army s interventionism has never allowed democracy to flourish in the country to a point where informed voters could truly understand the significance of the electoral process. That all civilian governments are incompetent in handling the challenges facing Pakistan and in turn fertile grounds for corruption and nepotism is a self-fulfilling prophecy that has been paving way for the Army s stranglehold over the country over the past seven decades. This is the argument that one would expect to echo from the PML-N over the next 10 months as it relies on the victim card against the conspiracy of external factors to continue to self-identify as democracy itself. Read more Shahid Khaqan Abbasi elected as Pakistan s new prime minister How Pakistan s Prime Minister Nawaz Sharif was brought down by a font And the nomination of Shahbaz Sharif whose blatant confrontation with the intelligence chief last year instigated a civil-military crisis that sent two senior PML-N leaders packing would reaffirm the party s alignment in opposition to the military establishment. The ruling family are sending clear message across to their voters the opposition parties and indeed the senior Army leadership: that the Sharifs aren t going anywhere. But this stubbornness to cling on to the party name is as damaging to democracy in the country as the soft coup currently in play. Whether or not that s equally detrimental to Pakistan s larger interests depends on what the Sharifs do with the continuity they re seeking. Either way this doctrine of necessity being used to squash actual democracy counterfeits the arguments that Army leaders have historically presented to overthrow elected leaders in Pakistan. More about: Pakistan Nawaz Sharif Imran Khan Reuse content Islamabad: Shahid Khaqan Abbasi Pakistan s interim Prime Minister is a long-time loyalist of ousted premier Nawaz Sharif and one of the wealthiest parliamentarians in the country.Abbasi 58 hails from the famous hill resort of Murree in Rawapindi district of Punjab province and was minister for petroleum in the ousted government.A die-hard supporter of Sharif he was elected Prime Minister by Pakistan s National Assembly and put up a strong defence of the ousted leader saying that he may have been disqualified by the Supreme Court but remains the people s premier .Sharif s Pakistan Muslim League-Nawaz (PML-N) nominated Abbasi as the interim Prime Minister until Sharif s brother and Punjab province chief minister Shehbaz Sharif is elected as a National Assembly member. He was the part of Sharif s team which was tasked to address the energy crisis in the country.He is a true loyalist of Sharif and stood with him when his government was toppled in 1999 by former Pakistani military dictator Pervez Musharraf.Abbasi who was imprisoned after the coup spent two years in jail.But unlike many other colleagues of Sharif Abbasi remained steadfast and did not switch sides. It was one of the reasons that Sharif chose him as the interim leader.Abbasi an electrical engineer with a master s degree from https://www.slideshare.net/goodnightquotes George Washington University joined politics rather abruptly after his father Khaqan Abbasi was killed on April 10 1988 when his car was hit by a missile after Ojhri Camp arms depot disaster in Rawalpindi.His father was the minister for production in the cabinet of then Prime Minister Muhammad Khan Junejo.Abbasi has been elected at least six times (1988 1990 1993 1997 2008 and 2013) as a member of the parliament and was defeated just once in 2002 when he lost to Pakistan People s Party candidate Ghulam Murtaza Satti.After winning elections in 1990 for the second time he was made the parliamentary secretary for defence.After the 1993 general elections he served as the chairman of the National Assembly s Standing Committee on Defence.Abbasi was elected for the fourth time in 1997 and served as the Chairman of Pakistan International Airlines from 1997 to 1999 during Nawaz Sharif s second term. He briefly held the positions of Minister for Commerce and Ministry of Defence Production in former prime minister Yousuf Raza Gilani s government in 2008 after the election but later resined as his PMLN party parted ways with the PPP.Earlier after completing his education he worked in the US and Saudi Arabia.Considered as one of the wealthiest parliamentarians in Pakistan he set up his Air Blue airlines in Pakistan in 2003 and served as its chairman till 2007. The airlines is still operating successfully. Photo Shahid Khaqan Abbasi center on Monday outside Parliament in Islamabad a day before his election as prime minister of Pakistan. The Supreme Court forced out his predecessor. Credit Anjum Naveed/Associated Press ISLAMABAD Pakistan Shahid Khaqan Abbasi a politician educated in the United States was elected prime minister of Pakistan on Tuesday. Parliament held a special election to replace his predecessor and mentor who was disqualified on corruption charges.Here is what you need to know about Pakistan s new leader.A Staunch LoyalistA steadfast ally of three-time Prime Minister Nawaz Sharif Mr. Abbasi 58 was named interim prime minister last week after the Supreme Court disqualified Mr. Sharif from office and he was forced to resign.Mr. Abbasi has gone to prison for his political patron. He spent two years behind bars after a 1999 coup in which Mr. Sharif was overthrown by Gen. Pervez Musharraf. Mr. Abbasi at the time was pressured by the military to testify against Mr. Sharif but he refused and was jailed. He was later acquitted.That loyalty to Mr. Sharif was later repaid with a high-profile cabinet position when the ousted leader returned to power in 2013. It is assumed that Mr. Abbasi is holding the office until Mr. Sharif s brother Shehbaz Sharif the chief minister of Punjab Province wins a seat in Parliament in a coming by-election and can become prime minister. Photo Mr. Abbasi rear right leaving court in Karachi Pakistan in 1999. He was among the allies of Nawaz Sharif who were convicted in the aftermath of the coup that ended Mr. Sharif s second run as prime minister. Credit Zia Mazhar/Associated Press A Long CareerMr. Abbasi is a member of the governing party the Pakistan Muslim League-Nawaz. He has been elected to Parliament six times losing an election only once. Continue reading the main story ISLAMABAD: Pakistan s new Prime Minister Shahid Khaqan Abbasi formed his cabinet on Friday filling it with his toppled predecessor Nawaz Sharif s aides and allies. It also included the first Hindu in a Pakistan government in more than 20 years Darshan Lal. The reshuffle was aimed at bolstering support for the ruling Pakistan Muslim League-Nawaz (PML-N) ahead of the general elections in mid-2018 with President Mamnoon Hussain administering the oath of office to 47-member cabinet that included 28 federal and 19 state ministers in a televised ceremony at his official residence. Read this story in Gujarati Darshan Lal would head coordination between four Pakistani provinces a government official said. Lal 65 is a practising doctor from Mirpur Mathelo town in Ghotki district of Sindh. In 2013 he was elected to the national assembly for the second time on PML-N ticket on a reserved seat for minorities. Khawaja Muhammad Asif minister for defence and power in previous cabinet was appointed the country s new foreign minister. Pakistan was without a foreign minister since Sharif became PM in 2013. The last foreign minister was Hina Rabbani Khar. Read this story in Marathi No decision has been made yet on whether Abbasi will remain the PM till the 2018 elections or step down after Shahbaz becomes eligible to take over after winning a by-election as previously decided. PML-N leadership is unsure about Shahbaz s resignation as his departure from Punjab could weaken the party s grip over the country s most powerful and populated province. Pakistan s mix of political parties has often ensured that whoever wins Punjab forms the central government. To strengthen the party s position in Punjab Abbasi has added five politicians from prominent families that command huge vote banks in the south of the region seen as pivotal to the next poll. Read this story in Malayalam The reshuffle saw Sharif s close aide Ishaq Dar resume his earlier role as finance minister despite a criminal investigation ordered against him by the Supreme Court in the Panama leaks. With ex-home minister Chauddhry Nisar Ali Khan reluctant to retain his post the interior ministry went to Ahsan Iqbal head of a commission tasked with building the 57 billion China-Pakistan Economic corridor. The Pakistan Supreme Court had disqualified former Prime Minister Nawaz Sharif from office over Panama Papers leaks last week following which Abbasi (former petroleum minister) took over. Abbasi a staunch Nawaz ally reportedly finalised the names and portfolios of the cabinet ministers after close consultation with the leader-in-exile and his younger brother Shahbaz Sharif who is the Punjab province chief minister. Read this story in Bengali By: Express Web Desk | New Delhi | Published:August 5 2017 11:28 am Newly-elected Prime Minister of Pakistan Shahid Khaqan Abbasi takes oath from Pakistani President Mamnoon Hussain at the Presidential palace in Islamabad Pakistan Tuesday Aug. 1 2017. AP/PTI Related News Shehbaz Sharif likely to miss opportunity to become Pakistan s Prime MinisterPakistan increasing infiltration efforts high number of casualties across border: Arun JaitleyGame of dronesAfter a span of 20 years a Hindu politician Darshan Lal is set to take the role of a cabinet minister in Pakistan. The decision was announced on Friday as the new Prime Minister Shahaid Khaqan Abbasi formulated his cabinet. According to a government official cited by news agency Reuters Abbasi has appointed 65-year old Lal to lead coordination between four Pakistan provinces. Lal reportedly used to practice as a doctor in Mirpur Mathelo town in Ghotki district of Sindh province. Lal was elected to the national assembly for the second time in 2013 on a Pakistan Muslim League (N) ticket under the minority quota. Meanwhile Abbasi filled his cabinet with aides and allies of ousted PM Nawaz Sharif aiming to boost the support for the ruling PML-N government just before the 2018 general elections. Pakistan President Mamnoon Hussain administered oath to 47 cabinet ministers in a televised swearing-in ceremony. The cabinet comprises of 28 federal and 19 state ministers. In spite of the on-going criminal investigation launched against him by Supreme Court Ishaq Dar returned to take back his position as finance minister. Khawaja Asif a close ally of Sharif who had earlier controlled defense and power ministries was appointed as the Foreign Minister. According to analysts cited by Reuters the size of the cabinet has been doubled keeping the upcoming generals in mind. It s a massive cabinet. It shows that it s all about the next election Pakistani writer and analyst Zahid Hussain said. (With inputs from Reuters) For all the latest Pakistan News download Indian Express App IE Online Media Services Pvt Ltd More Related News Pakistan Oppn leader Imran Khan faces parliamentary probe into sexual harassment Pakistan increasing attempts to push terrorists into Kashmir: Govt Tags: Darshan Lal Pakistan Shahid Khaqan Abbasi GginololoyaAug 5 2017 at 3:36 pmCan not believe a Hindu in Pakistan s Government.Reply KKMAug 5 2017 at 2:56 pmPakistan has become secular and India is going in other way. Awaiting for Tolerance India where all live peaceful and harmony. Let us throw the dirty politicians (BJP / RSS / Shiv Sena) who wants to do their business in the name of ReligionReply KKP PillaiAug 5 2017 at 2:42 pmIE CORRECTION PLS..... INDIAN EXPRESS WRONG PRINTING... LAST PARA UPCOMING GENERALS ???? !!!!! OR UPCOMING GENERAL ELECTIONS IN MIND ???Reply SSumitAug 5 2017 at 2:06 pmAfter 20 years a Hindu minister!!! Here in India after breaking Hindu majority Bharat nation in to three parts and two parts were given to RELIGION OF PIECE on the basis of religion and remaining part India had been declared as India is under common quota and any religion can take it away. Muslims were President Vice President cabinet ministers Chief Ministers and even their Khan Cross party ruled this country for more than half a century on behalf of Muslims. This is the story in India. What is for Hindu religion and India?Nothing. Nothing.Reply AAnmolAug 5 2017 at 1:52 pmWorld is moving forward and has accepted the advantage of diversity. Sanghis are taking India back by shunning diversity and spreading hate.ReplyKKP PillaiAug 5 2017 at 2:44 pmConsult a psycho.. !!Reply PPartha MajumderAug 5 2017 at 1:22 pmin bangladesh and pakistan there is almost no hindu representing cricket team parliament etc. why ? hindus are not layek there ? what common sence says ? can the smell of a  https://500px.com/gdnther/about rotten egg can be confined by covering with a bowl ? our murkh intellectuals are mostly from hindu community. if higher education destroys basic sence freeze their certificates.Reply SsecureAug 5 2017 at 12:06 pmShame on Modi anhatemonger of Muslim learn a lesson from Pakistan they just have 2 Hindus and one cabinet Ministry and in India Muslims are 30 no Cabinet Minister.ReplyGGAug 5 2017 at 12:29 pmShame on you. What does it have to do with hate monger? The capable popular and elected move ahead. Simple as that. You learnt anything else from Pakistan?ReplyPPartha MajumderAug 5 2017 at 1:13 pmmurkh ho to aisa.CChandu ShahAug 5 2017 at 1:13 pmWho is the Vice President?Reply BBhadrapati DeviAug 5 2017 at 11:37 amIt is good news of electing a Hindu in the cabinet Ministry in Pakistan. It is showing secular credential of Pakistan. Pakistan economic prosperity may have buried all fundamentalism ideology under CPEC.Reply Load More Comments

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